Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
The maintenance of eukaryotic genomes in a complete and undamaged state is critical for any tightly regulated DNA process such as replication and transcription to function efficiently. With DNA damage response and repair systems predominantly slow, cells must be equipped with factors that work at th...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/137770 |