Loss of Parkin impairs mitochondrial function and leads to muscle atrophy

Parkinson's disease is a neurodegenerative disease characterized by tremors, muscle stiffness, and muscle weakness. Molecular genetic analysis has confirmed that mutations in PARKIN and PINK1 genes, which play major roles in mitochondrial quality control and mitophagy, are frequently associated...

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Hlavní autoři: Peker, Nesibe, Donipadi, Vinay, Sharma, Mridula, McFarlane, Craig, Kambadur, Ravi
Další autoři: School of Biological Sciences
Médium: Journal Article
Jazyk:English
Vydáno: 2020
Témata:
On-line přístup:https://hdl.handle.net/10356/138111