Loss of Parkin impairs mitochondrial function and leads to muscle atrophy

Parkinson's disease is a neurodegenerative disease characterized by tremors, muscle stiffness, and muscle weakness. Molecular genetic analysis has confirmed that mutations in PARKIN and PINK1 genes, which play major roles in mitochondrial quality control and mitophagy, are frequently associated...

Повний опис

Бібліографічні деталі
Автори: Peker, Nesibe, Donipadi, Vinay, Sharma, Mridula, McFarlane, Craig, Kambadur, Ravi
Інші автори: School of Biological Sciences
Формат: Journal Article
Мова:English
Опубліковано: 2020
Предмети:
Онлайн доступ:https://hdl.handle.net/10356/138111