Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

The dynamic interaction of the N- and C-terminal domains of mycobacterial F-ATP synthase subunit ε is proposed to contribute to efficient coupling of H+-translocation and ATP synthesis. Here, we investigate crosstalk between both subunit ε domains by introducing chromosomal atpC missense mutations i...

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Bibliographic Details
Main Authors: Saw, Wuan-Geok, Wu, Mu-Lu, Ragunathan, Priya, Biuković, Goran, Lau, Aik-Meng, Shin, Joon, Harikishore, Amaravadhi, Cheung, Chen-Yi, Hards, Kiel, Sarathy, Jickky Palmae, Bates, Roderick Wayland, Cook, Gregory M., Dick, Thomas, Grüber, Gerhard
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences::Biochemistry
Science::Biological sciences::Molecular biology
Bacteriology
Pathogens
Online Access:https://hdl.handle.net/10356/138536

Internet

https://hdl.handle.net/10356/138536

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