Regulation of primary cilia formation and hedgehog signalling by a PDZ domain protein with function in melanoma growth
The Hedgehog signalling pathway is one of the key developmental pathways essential for cell fate specification, proliferation and tissue patterning. Aberrant activation of the pathway contributes to cancer cell proliferation and survival. The lab has identified GIPC3, a PDZ domain containing protein...
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Format: | Final Year Project (FYP) |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/138620 |