A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE Gram‐negative bacteria

A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE Gram‐negative bacteria

Carbapenem‐resistant Gram‐negative bacteria (GNB) are heading the list of pathogens for which antibiotics are the most critically needed. Many antibiotics are either unable to penetrate the outer‐membrane or are excluded by efflux mechanisms. Here, we report a cationic block β‐peptide (PAS8‐b‐PDM12)...

Full description

Bibliographic Details
Main Authors: Si, Zhangyong, Lim, Hui Wen, Tay, Moon Yue Feng, Du, Yu, Ruan, Lin, Qiu, Haofeng, Zamudio-Vazquez, Rubí, Reghu, Sheethal, Chen, Yahua, Tiong, Wen Shuo, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Zhu, Yabin, Gan, Yunn-Hwen, Chi, Robin Yonggui, Duan, Hongwei, Bazan, Guillermo C., Greenberg, E. Peter, Chan-Park, Mary Bee Eng, Pethe, Kevin
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Engineering::Bioengineering
Antimicrobial Resistance
β-peptides
Online Access:https://hdl.handle.net/10356/138782

Internet

https://hdl.handle.net/10356/138782

Similar Items