A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE Gram‐negative bacteria

A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE Gram‐negative bacteria

Carbapenem‐resistant Gram‐negative bacteria (GNB) are heading the list of pathogens for which antibiotics are the most critically needed. Many antibiotics are either unable to penetrate the outer‐membrane or are excluded by efflux mechanisms. Here, we report a cationic block β‐peptide (PAS8‐b‐PDM12)...

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Bibliografische gegevens
Hoofdauteurs: Si, Zhangyong, Lim, Hui Wen, Tay, Moon Yue Feng, Du, Yu, Ruan, Lin, Qiu, Haofeng, Zamudio-Vazquez, Rubí, Reghu, Sheethal, Chen, Yahua, Tiong, Wen Shuo, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Zhu, Yabin, Gan, Yunn-Hwen, Chi, Robin Yonggui, Duan, Hongwei, Bazan, Guillermo C., Greenberg, E. Peter, Chan-Park, Mary Bee Eng, Pethe, Kevin
Andere auteurs: School of Chemical and Biomedical Engineering
Formaat: Journal Article
Taal:English
Gepubliceerd in: 2020
Onderwerpen:
Engineering::Bioengineering
Antimicrobial Resistance
β-peptides
Online toegang:https://hdl.handle.net/10356/138782

Internet

https://hdl.handle.net/10356/138782

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