Discovery, biosynthesis and antifungal mechanism of the polyene-polyol meijiemycin

Discovery, biosynthesis and antifungal mechanism of the polyene-polyol meijiemycin

Produced by a newly isolated Streptomycetes strain, meijiemycin is a gigantic linear polyene-polyol that exhibits structural features not seen in other members of the polyene-polyol family. We propose a biosynthetic mechanism and demonstrate that meijiemycin inhibits hyphal growth by inducing the ag...

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Bibliographic Details
Main Authors: Low, Zhen Jie, Xiong, Juan, Xie, Ying, Ma, Guang-Lei, Saw, Howard, Tran, Hoa Thi, Wong, Soo Lin, Pang, Li Mei, Fong, July, Lu, Peng, Hu, Jin-Feng, Liang, Yang, Miao, Yansong, Liang, Zhao-Xun
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences::Biochemistry
Science::Biological sciences::Microbiology
Natural Product
Anti-fungal Agent
Online Access:https://hdl.handle.net/10356/138959

Internet

https://hdl.handle.net/10356/138959

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