Discovery, biosynthesis and antifungal mechanism of the polyene-polyol meijiemycin
Produced by a newly isolated Streptomycetes strain, meijiemycin is a gigantic linear polyene-polyol that exhibits structural features not seen in other members of the polyene-polyol family. We propose a biosynthetic mechanism and demonstrate that meijiemycin inhibits hyphal growth by inducing the ag...
Main Authors: | Low, Zhen Jie, Xiong, Juan, Xie, Ying, Ma, Guang-Lei, Saw, Howard, Tran, Hoa Thi, Wong, Soo Lin, Pang, Li Mei, Fong, July, Lu, Peng, Hu, Jin-Feng, Liang, Yang, Miao, Yansong, Liang, Zhao-Xun |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/138959 |
Similar Items
-
Sungeidines from a non-canonical enediyne biosynthetic pathway
by: Low, Zhen Jie, et al.
Published: (2020) -
Structural and biochemical study of Candida albicans polarisomal proteins
by: Loh, Zhi Yang
Published: (2021) -
Identification and characterization of novel chemical scaffolds to overcome drug resistance in malaria
by: Tay, Donald Wen Jun
Published: (2020) -
Discovery and biosynthesis of specialized metabolites produced by an indigenous streptomyces strain
by: Candra, Hartono
Published: (2022) -
Optimizing antifungal properties of tetrabranched peptide B4010.
by: Siti Radiah Safie.
Published: (2012)