Cobalt-catalyzed directed : ortho-methylation of arenes with methyl tosylate

A cobalt-catalyzed directed ortho C-H methylation reaction of arenes has been achieved using readily available methyl tosylate as a methylating agent. An in situ-generated cobalt-N-heterocyclic carbene catalyst in combination with neopentylmagnesium bromide promotes the methylation at room temperatu...

Full description

Bibliographic Details
Main Authors: Sun, Qiao, Yoshikai, Naohiko
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139028