Optimisation of modRNA gene delivery and the FUCCI mouse model for cardiomyocyte proliferation

The human heart is known to have limited regenerative capacity, with minimal proliferation of pre-existing cardiomyocytes. After a myocardial infarction, extensive cardiomyocyte death occurs, resulting in heart failure. Thus, efforts have been made to identify remaining proliferative cardiomyocytes....

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Bibliographic Details
Main Author: Hew, Rachel Jia Yi
Other Authors: -
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139952