Optimisation of modRNA gene delivery and the FUCCI mouse model for cardiomyocyte proliferation
The human heart is known to have limited regenerative capacity, with minimal proliferation of pre-existing cardiomyocytes. After a myocardial infarction, extensive cardiomyocyte death occurs, resulting in heart failure. Thus, efforts have been made to identify remaining proliferative cardiomyocytes....
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Format: | Final Year Project (FYP) |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/139952 |