Chromatin topology defines cell identity and phenotypic transition in human cancer and fungal pathogen
Higher-order chromatin organization plays an important role in epigenetic regulation of gene expression. Chromatin topology has been increasingly recognized to define cellular identity. Alterations in chromatin conformation are often associated with phenotypic changes and can even lead to cellular s...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/140893 |