Prolonged hypoxia promotes enrichment of cytosolic EZH2 in breast cancer stem cells via a HIF-1α-independent mechanism

Cancer stem cells (CSCs) make up a small subpopulation of the entire tumour. They have the ability to self-renew as well as differentiate into the cells that make up the bulk tumour. Previously, we have demonstrated that EZH2 is highly enriched in the cytosol of breast cancer stem cells (BCSCs), res...

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Bibliographic Details
Main Author: Law, Daniel Cheng Lui
Other Authors: Su I-Hsin
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142015