Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination

Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination

The loss of oligodendrocytes (OLs) and subsequently myelin sheaths following injuries or pathologies in the CNS leads to debilitating functional deficits. Unfortunately, effective methods of remyelination remain limited. Here, we present a scaffolding system that enables sustained non-viral delivery...

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Bibliographic Details
Main Authors: Milbreta, Ulla, Lin, Junquan, Pinese, Coline, Ong, William, Chin, Jiah Shin, Shirahama, Hitomi, Mi, Ruifa, Williams, Anna, Bechler, Marie E., Wang, Jun, ffrench-Constant, Charles, Hoke, Ahmet, Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Engineering::Bioengineering
Myelination
MicroRNA
Online Access:https://hdl.handle.net/10356/142055

Internet

https://hdl.handle.net/10356/142055

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