Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates
The glucagon receptor (GCGR) is an emerging target in anti-diabetic therapy. Reliable biomarkers for in vivo activity on the GCGR, in the setting of dual glucagon-like peptide 1/glucagon (GLP-1/GCG) receptor agonism, are currently unavailable. Here, we investigated [68Ga]Ga-DO3A-S01-GCG as a biomark...
| Main Authors: | , , , , , , , , , , , , , |
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| 其他作者: | |
| 格式: | Journal Article |
| 语言: | English |
| 出版: |
2020
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| 主题: | |
| 在线阅读: | https://hdl.handle.net/10356/142352 |