Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases

For over a half-century the anti-malarial drug chloroquine (CQ) has been used as a therapeutic agent, alone or in combination, to treat autoimmune diseases. However, neither the underlying mechanism(s) of action nor their molecular target(s) are well defined. The orphan nuclear receptor Nurr1 (also...

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Bibliographic Details
Main Authors: Park, Tae-Yoon, Jang, Yongwoo, Kim, Woori, Shin, Joon, Toh, Hui Ting, Kim, Chun-Hyung, Yoon, Ho Sup, Leblanc, Pierre, Kim, Kwang-Soo
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142409