Active site CP-loop dynamics modulate substrate binding, catalysis, oligomerization, stability, over-oxidation and recycling of 2-Cys Peroxiredoxins
Peroxiredoxins (Prxs) catalyse the rapid reduction of hydrogen peroxide, organic hydroperoxide and peroxynitrite, using a fully conserved peroxidatic cysteine (CP) located in a conserved sequence Pxxx(T/S)xxCP motif known as CP-loop. In addition, Prxs are involved in cellular signaling pathways and...
| Κύριοι συγγραφείς: | , , , |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Journal Article |
| Γλώσσα: | English |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://hdl.handle.net/10356/142461 |