Carbene-catalyzed dynamic kinetic resolution for asymmetric access to phthalidyl esters and benzofuranone derivatives

In this thesis, we have demonstrated two dynamic kinetic resolution strategies enabled by N-heterocyclic carbene. Firstly, asymmetric acylation of hydroxyphthalides through N-heterocyclic carbene catalyzed dynamic kinetic resolution approach has been achieved. In addition, enantioselective modificat...

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Bibliographic Details
Main Author: Majhi, Pankaj Kumar
Other Authors: Robin Yonggui Chi
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142580