Inactivation of the pgmA gene in Streptococcus mutans significantly decreases biofilm-associated antimicrobial tolerance

Screening of a Streptococcus mutans mutant library indicated that pgmA mutants displayed a reduced biofilm-associated tolerance toward gentamicin. The biofilms formed by the S. mutanspgmA mutant also displayed decreased tolerance towards linezolid and vancomycin compared to wild-type biofilms. On th...

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Bibliographic Details
Main Authors: Nilsson, Martin, Givskov, Michael, Twetman, Svante, Tolker-Nielsen, Tim
Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142821