Inactivation of the pgmA gene in Streptococcus mutans significantly decreases biofilm-associated antimicrobial tolerance

Screening of a Streptococcus mutans mutant library indicated that pgmA mutants displayed a reduced biofilm-associated tolerance toward gentamicin. The biofilms formed by the S. mutanspgmA mutant also displayed decreased tolerance towards linezolid and vancomycin compared to wild-type biofilms. On th...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Nilsson, Martin, Givskov, Michael, Twetman, Svante, Tolker-Nielsen, Tim
Weitere Verfasser: Singapore Centre for Environmental Life Sciences and Engineering
Format: Journal Article
Sprache:English
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://hdl.handle.net/10356/142821