Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration

Mounting evidence indicates that the polygenic basis of late-onset Alzheimer's disease can be harnessed to identify individuals at greatest risk for cognitive decline. We have previously developed and validated a polygenic hazard score comprising of 31 single nucleotide polymorphisms for predic...

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Bibliografiska uppgifter
Huvudupphovsmän: Tan, Chin Hong, Bonham, Luke W., Fan, Chun Chieh, Mormino, Elizabeth C., Sugrue, Leo P., Broce, Iris J., Hess, Christopher P., Yokoyama, Jennifer S., Rabinovici, Gil D., Miller, Bruce L., Yaffe, Kristine., Schellenberg, Gerard D., Kauppi, Karolina, Holland, Dominic, McEvoy, Linda K., Kukull, Walter A., Tosun, Duygu, Weiner, Michael W., Sperling, Reisa A., Bennett, David A., Hyman, Bradley T., Andreassen, Ole A., Dale, Anders M., Desikan, Rahul S.
Övriga upphovsmän: School of Social Sciences
Materialtyp: Journal Article
Språk:English
Publicerad: 2020
Ämnen:
Social sciences::Psychology
Polygenic Hazard Score
Amyloid
Länkar:https://hdl.handle.net/10356/142983

Internet

https://hdl.handle.net/10356/142983

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