Ligase-controlled cyclo-oligomerization of peptides

A biomimetic one-step ligase-catalyzed cyclo-oligomerization mediated by butelase 1, an Asn/Asp-specific ligase, is introduced that is time-, concentration-, length-, and sequence-dependent. This reaction yields cyclic mono-, di-, tri-, and tetramers from peptide precursors containing 3-15 amino aci...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Hemu, Xinya, Zhang, Xiaohong, Tam, James P.
מחברים אחרים: School of Biological Sciences
פורמט: Journal Article
שפה:English
יצא לאור: 2020
נושאים:
גישה מקוונת:https://hdl.handle.net/10356/143886