Enzymatic and structural insights into the mycobacterial alkylhydroperoxide reductase subunit C and repurposing of an antimalaria compound inhibiting the mycobacterial cytochrome BCC oxidase for tuberculosis disease
Tuberculosis (TB) is one of the leading contagious diseases that results in mortality. Treatment with antibiotics has been applied for TB however, with new forms of antibiotic resistance emerging, difficulty in treatment of TB was detected. In this study, alkylhydroperoxide reductase subunit C (MtAh...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/143914 |