Minimum structural requirements for BMP-2-binding of heparin oligosaccharides

Minimum structural requirements for BMP-2-binding of heparin oligosaccharides

Bone morphogenetic proteins (BMPs) are essential during tissue repair and remodeling after injury. Glycosaminoglycan (GAG) sugars are known to enhance BMP activity in vitro and in vivo; here the interactions of BMP-2 with various glycosaminoglycan classes were compared and shown to be selective for...

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Bibliographic Details
Main Authors: Smith, Raymond A. A., Murali, Sadasivam, Rai, Bina, Lu, Xiaohua, Lim, Zophia Xue Hui, Lee, Jaslyn J. L., Nurcombe, Victor, Cool, Simon M.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Medicine
Heparin
Glycosaminoglycan
Online Access:https://hdl.handle.net/10356/143973

Internet

https://hdl.handle.net/10356/143973

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