Diazoalkane decay kinetics from UVA-active protein labelling molecules : trifluoromethyl phenyl diazirines

Trifluoromethyl phenyl diazirine (TPD) molecules are relatively stable carbene precursors, that readily form carbon covalent bonds with proteins. The stability of the diazoalkane intermediates is unknown, as are the factors which control carbene/diazoalkane ratios. This leads to incomplete carbene i...

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Bibliographic Details
Main Authors: Djordjevic, Ivan, Wicaksono, Gautama, Solic, Ivan, Steele, Terry W. J.
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/144265