An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin

Reptin is a member of the AAA+ superfamily whose members can exist in equilibrium between monomeric apo forms and ligand bound hexamers. Inter-subunit protein-protein interfaces that stabilize Reptin in its oligomeric state are not well-defined. A self-peptide binding assay identified a protein-pept...

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Bibliographic Details
Main Authors: Coufalova, Dominika, Remnant, Lucy, Hernychova, Lenka, Muller, Petr, Healy, Alan, Kannan, Srinivasaraghavan, Westwood, Nicholas, Verma, Chandra Shekhar, Vojtesek, Borek, Hupp, Ted R., Houston, Douglas R.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Engineering::Bioengineering
Reptin
Protein
Online Access:https://hdl.handle.net/10356/144645

Internet

https://hdl.handle.net/10356/144645

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