METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing

N6-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N6,2′-O-dimethyladenosine (m6Am). Identification of the methyltransferase responsible for m6Am catalysis has accelerated studies on the function of m6Am in RNA processing. While m6Am is generally found in the f...

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Bibliographic Details
Main Authors: Goh, Yeek Teck, Koh, Casslynn W. Q., Sim, Donald Yuhui, Roca, Xavier, Goh, W. S. Sho
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145157