Towards understanding and applications of antisense oligonucleotides
Antisense oligonucleotides (ASOs), which are synthetic single-stranded nucleic acids, could enter living cells, hybridize to RNAs and inhibit gene expression. This approach could potentially lead to desired alterations of cellular characteristics, and has been under intensive investigations. This th...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2020
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Online Access: | https://hdl.handle.net/10356/145300 |