Towards understanding and applications of antisense oligonucleotides

Antisense oligonucleotides (ASOs), which are synthetic single-stranded nucleic acids, could enter living cells, hybridize to RNAs and inhibit gene expression. This approach could potentially lead to desired alterations of cellular characteristics, and has been under intensive investigations. This th...

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Bibliographic Details
Main Author: Nguyen, Le Tuan Anh
Other Authors: Phan Anh Tuan
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145300