Development of mucus-penetrating antibiotic and quorum sensing inhibitor nanoparticle complex for bronchiectasis therapy

Bronchiectasis is a chronic respiratory disease characterized by permanent and irreversible dilatation of the airways caused by a vicious cycle of infection and inflammation, leading to the loss of lung function, morbidity, and mortality. Early results suggested inhaled ciprofloxacin (CIP) as a prom...

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Bibliographic Details
Main Author: Tran, The Thien
Other Authors: Kunn Hadinoto Ong
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145374