Investigating super-enhancer-associated chromatin interactions at the HOXA9-MEIS1 oncogene signalling axis in myeloid leukaemia
Myeloid leukaemia is a form of blood cancer that is characterised by a block in haematopoietic stem cell differentiation and uncontrolled cell proliferation. HOXA9 and MEIS1 are two commonly overexpressed oncogenes that are associated with poor prognoses in myeloid leukaemia patients. However, our u...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/145566 |