Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines

Background: Hi-C and its variant techniques have been developed to capture the spatial organization of chromatin. Normalization of Hi-C contact map is essential for accurate modeling and interpretation of high-throughput chromatin conformation capture (3C) experiments. Hi-C correction tools were ori...

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Bibliographic Details
Main Authors: Ahmed Ibrahim Samir Khalil, Siti Rawaidah Mohammad Muzaki, Chattopadhyay, Anupam, Sanyal, Amartya
Other Authors: School of Computer Science and Engineering
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/145880