Scaffold-based delivery of CRISPR/Cas9 ribonucleoproteins for genome editing

The simple and versatile CRISPR/Cas9 system is a promising strategy for genome editing in mammalian cells. Generally, the genome editing components, namely Cas9 protein and single-guide RNA (sgRNA), are delivered in the format of plasmids, mRNA or ribonucleoprotein (RNP) complexes. In particular, no...

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Bibliographic Details
Main Authors: Chooi, Wai Hon, Chin, Jiah Shin, Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/145891