Defining essential enhancers for pluripotent stem cells using a features-oriented CRISPR-Cas9 screen

Defining essential enhancers for pluripotent stem cells using a features-oriented CRISPR-Cas9 screen

cis-regulatory elements (CREs) regulate the expression of genes in their genomic neighborhoods and influence cellular processes such as cell-fate maintenance and differentiation. To date, there remain major gaps in the functional characterization of CREs and the identification of their target genes...

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Bibliographic Details
Main Authors: Wang, Hao Fei, Warrier, Tushar, Farran, Chadi A., Zheng, Zi Hao, Xing, Qiao Rui, Fullwood, Melissa Jane, Zhang, Li-Feng, Li, Hu, Xu, Jian, Lim, Tit-Meng, Loh, Yuin-Han
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
CRISPR Screen
OCT4-bound
Online Access:https://hdl.handle.net/10356/145979

Internet

https://hdl.handle.net/10356/145979

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