The bactericidal fatty acid mimetic 2CCA-1 selectively targets pneumococcal extracellular polyunsaturated fatty acid metabolism

The bactericidal fatty acid mimetic 2CCA-1 selectively targets pneumococcal extracellular polyunsaturated fatty acid metabolism

Streptococcus pneumoniae, a major cause of pneumonia, sepsis, and meningitis worldwide, has the nasopharynges of small children as its main ecological niche. Depletion of pneumococci from this niche would reduce the disease burden and could be achieved using small molecules with narrow-spectrum anti...

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Bibliographic Details
Main Authors: Reithuber, Elisabeth, Nannapaneni, Priyanka, Rzhepishevska, Olena, Lindgren, Anders E. G., Ilchenko, Oleksandr, Normark, Staffan, Almqvist, Fredrik, Henriques-Normark, Birgitta, Mellroth, Peter
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Streptococcus Pneumoniae
Pneumococci
Online Access:https://hdl.handle.net/10356/146001

Internet

https://hdl.handle.net/10356/146001

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