Duplex formation in a G-quadruplex bulge

Beyond the consensus definition of G-quadruplex-forming motifs with tracts of continuous guanines, G-quadruplexes harboring bulges in the G-tetrad core are prevalent in the human genome. Here, we study the incorporation of a duplex hairpin within a bulge of a G-quadruplex. The NMR solution structure...

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Bibliographic Details
Main Authors: Ngoc Nguyen, Thi Quynh, Lim, Kah Wai, Phan, Anh Tuân
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/146278