Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites
Background: The human proteins TMTC1, TMTC2, TMTC3 and TMTC4 have been experimentally shown to be components of a new O-mannosylation pathway. Their own mannosyl-transferase activity has been suspected but their actual enzymatic potential has not been demonstrated yet. So far, sequence analysis of T...
Main Authors: | , , , , , , |
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Outros Autores: | |
Formato: | Journal Article |
Idioma: | English |
Publicado em: |
2021
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Assuntos: | |
Acesso em linha: | https://hdl.handle.net/10356/146664 |