Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes
Background: Detection of DNA copy number alterations (CNAs) is critical to understand genetic diversity, genome evolution and pathological conditions such as cancer. Cancer genomes are plagued with widespread multi-level structural aberrations of chromosomes that pose challenges to discover CNAs of...
मुख्य लेखकों: | , , , |
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अन्य लेखक: | |
स्वरूप: | Journal Article |
भाषा: | English |
प्रकाशित: |
2021
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विषय: | |
ऑनलाइन पहुंच: | https://hdl.handle.net/10356/146948 |