Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes

Background: Detection of DNA copy number alterations (CNAs) is critical to understand genetic diversity, genome evolution and pathological conditions such as cancer. Cancer genomes are plagued with widespread multi-level structural aberrations of chromosomes that pose challenges to discover CNAs of...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Ahmed Ibrahim Samir Khalil, Khyriem, Costerwell, Chattopadhyay, Anupam, Sanyal, Amartya
अन्य लेखक: School of Computer Science and Engineering
स्वरूप: Journal Article
भाषा:English
प्रकाशित: 2021
विषय:
ऑनलाइन पहुंच:https://hdl.handle.net/10356/146948