Cobalt-catalyzed N-O and C-C bond cleavage in 1,2-oxazetidines : solvent-controlled C-H aminomethylation and hydroxymethylation of heteroarenes

An efficient cobalt-catalyzed ring-opening reaction of bench-stable 1,2-oxazetidines with heteroarenes was unprecedentedly developed. The sustainable Cp *Co(III) catalyst enables a distinctive merger of C-H activation with concomitant N-O and C-C cleavages of 1,2-oxazetidine, leading to site-selecti...

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Bibliographic Details
Main Authors: Li, Song, Shi, Pengfei, Liu, Rui-Hua, Hu, Xu-Hong, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/147449