Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling
Talin critically controls integrin-dependent cell migration, but its regulatory role in skin dendritic cells (DCs) during inflammatory responses has not been investigated. Here, we show that talin1 regulates not only integrin-dependent Langerhans cell (LC) migration, but also MyD88-dependent Toll-li...
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2021
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/147535 https://rupress.org/jem/article/217/8/e20191810/151800/Talin1-controls-dendritic-cell-activation-by |