Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling

Talin critically controls integrin-dependent cell migration, but its regulatory role in skin dendritic cells (DCs) during inflammatory responses has not been investigated. Here, we show that talin1 regulates not only integrin-dependent Langerhans cell (LC) migration, but also MyD88-dependent Toll-li...

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Bibliographic Details
Main Authors: Lim, Thomas Jun Feng, Bunjamin, Maegan, Ruedl, Christiane, Su, I-hsin
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/147535
https://rupress.org/jem/article/217/8/e20191810/151800/Talin1-controls-dendritic-cell-activation-by