Towards understanding of PRC2 binding to RNA

Polycomb repressive complex 2 (PRC2) and its methylation of histone 3 at lysine 27 (H3K27me3) play a crucial role in epigenetic regulation of normal development and malignancy. Several factors regulate the recruitment of PRC2 and affects its chromatin modification function. Over the past years, emer...

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Bibliographic Details
Main Authors: Yan, Junli, Dutta, Bibek, Hee, Yan Ting, Chng, Wee-Joo
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/147827