Targeting telomerase in cancer cells using degrader-based platforms
Telomeres progressively shorten during each cell division as a result of the “end replication problem”. A hallmark of cancer is unrestricted cell proliferation, which correlates to the maintenance of telomere length through the activation of telomerase or telomerase-independent recombination mechani...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/148039 |