Enantioselective modification of sulfonamides and sulfonamide-containing drugs via carbene organic catalysis

Enantioselective modification of sulfonamides and sulfonamide-containing drugs via carbene organic catalysis

A carbene-catalyzed method for highly enantioselective modification of sulfonamides is disclosed. The reaction proceeds under mild conditions with broad substrate scope, wide functional group tolerance, and good to excellent yields. When multiple sulfonamides or amines are present in the same molecu...

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Bibliographic Details
Main Authors: Song, Runjiang, Liu, Yingguo, Majhi, Pankaj Kumar, Ng, Pei Rou, Hao, Lin, Xu, Jun, Tian, Weiyi, Zhang, Long, Liu, Hongmei, Zhang, Xinglong, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Chemistry
Sulfonamides
Non-covalent Interactions
Online Access:https://hdl.handle.net/10356/148228

Internet

https://hdl.handle.net/10356/148228

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