Development of ratiometric fluorescent pH nanoprobe to study endocytic uptake pathways of antisense oligonucleotides

Anti-sense oligonucleotides (ASOs) are single short strands of synthetic DNA/RNA designed to complement specific RNA sequences. Antisense therapy as a treatment option has received widespread consideration as only knowledge of a nucleotide sequence is necessary for drug design. However, one challeng...

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Bibliographic Details
Main Author: Liew, Donn Hou Feng
Other Authors: Phan Anh Tuan
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/148512