Development of ratiometric fluorescent pH nanoprobe to study endocytic uptake pathways of antisense oligonucleotides
Anti-sense oligonucleotides (ASOs) are single short strands of synthetic DNA/RNA designed to complement specific RNA sequences. Antisense therapy as a treatment option has received widespread consideration as only knowledge of a nucleotide sequence is necessary for drug design. However, one challeng...
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Format: | Final Year Project (FYP) |
Language: | English |
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Nanyang Technological University
2021
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Online Access: | https://hdl.handle.net/10356/148512 |