Metformin alters human host responses to Mycobacterium tuberculosis in healthy subjects

Metformin alters human host responses to Mycobacterium tuberculosis in healthy subjects

Background" Metformin, the most widely administered diabetes drug, has been proposed as a candidate adjunctive host-directed therapy for tuberculosis, but little is known about its effects on human host responses to Mycobacterium tuberculosis. Methods: We investigated in vitro and in vivo effe...

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Bibliographic Details
Main Authors: Lachmandas, Ekta, Eckold, Clare, Böhme, Julia, Koeken, Valerie A. C. M., Mardiana Marzuki, Blok, Bastiaan, Arts, Rob J. W., Chen, Jinmiao, Teng, Karen W. W., Ratter, Jacqueline, Smolders, Elise J., Van den Heuvel, Corina, Stienstra, Rinke, Dockrell, Hazel M., Newell, Evan, Netea, Mihai G., Singhal, Amit, Cliff, Jacqueline M., Van Crevel, Reinout
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Metformin
Tuberculosis
Online Access:https://hdl.handle.net/10356/149037

Internet

https://hdl.handle.net/10356/149037

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