Examining the practical limits of batch effect-correction algorithms : when should you care about batch effects?

Batch effects are technical sources of variation and can confound analysis. While many performance ranking exercises have been conducted to establish the best batch effect-correction algorithm (BECA), we hold the viewpoint that the notion of best is context-dependent. Moreover, alternative questions...

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Bibliographic Details
Main Authors: Zhou, Longjian, Sue, Andrew Chi-Hau, Goh, Wilson Wen Bin
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/150368