Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling

A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bioconjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins, and living cells under physiologi...

Full description

Bibliographic Details
Main Authors: Bi, Xiaobao, Yin, Juan, Rao, Chang, Balamkundu, Seetharamsing, Banerjee, Biplab, Zhang, Dingpeng, Zhang, Dawei, Dedon, Peter C., Liu, Chuan-Fa
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/150739