A 3D fiber-hydrogel based non-viral gene delivery platform reveals that microRNAs promote axon regeneration and enhance functional recovery following spinal cord injury

A 3D fiber-hydrogel based non-viral gene delivery platform reveals that microRNAs promote axon regeneration and enhance functional recovery following spinal cord injury

Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on overcoming the inhibitory microenvironment that surrounds lesion sites. Unfortunately, the mere modulation of the cell/tissue microenvironment is often insufficient to achieve desired functional recovery. Therefore...

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Bibliographic Details
Main Authors: Zhang, Na, Lin, Junquan, Lin, Vincent Po Hen, Milbreta, Ulla, Chin, Jiah Shin, Chew, Elaine Guo Yan, Lian, Michelle Mulan, Foo, Jia Nee, Zhang, Kunyu, Wu, Wutian, Chew, Sing Yian
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences::Cytology
Engineering::Chemical engineering::Biochemical engineering
Science::Biological sciences::Molecular biology
Hydrogel
RNA Interference
Neural Tissue Engineering
Electrospinning
RNA Sequencing
Online Access:https://hdl.handle.net/10356/150957

Internet

https://hdl.handle.net/10356/150957

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