Local regulation and function of importin-β1 in hippocampal neurons during transcription-dependent plasticity

Activity-dependent transcription is critical for the encoding of long-term memories. Regulated nuclear entry of soluble proteins is one method to relay synaptic signals to the nucleus to couple neuronal excitation with transcription. To date, the role of importin-β1 in nuclear shuttling of proteins...

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Bibliographic Details
Main Author: Lee, Yan Jun
Other Authors: CHNG Toh Hean
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/151287