Biological consequences of error during ribosome biogenesis
Rpl24, a eukaryotic 60S ribosomal protein, forms inter-subunit bridges. Lack of Rpl24 protein may weaken inter-subunit association, introducing problems during translation such as ribosome stalling. Ribosome stalling produces stalled polypeptides which accumulate to form toxic aggregates if undegrad...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/152343 |