Targeting thioredoxin reductase with organometallics

Targeting thioredoxin reductase with organometallics

The thioredoxin (Trx) system is a key antioxidant system to the regulation of oxidative stress in cells. Thioredoxin reductase (TrxR) is an enzyme which is central to the Trx system and is upregulated in cancer cells, making it a potential target in anti-cancer therapy. Its active site contains an S...

书目详细资料
主要作者:	Koh, Wei Xiang
其他作者:	Leong Weng Kee
格式:	Thesis-Doctor of Philosophy
语言:	English
出版:	Nanyang Technological University 2021
主题:	Science::Chemistry::Inorganic chemistry::Metals Science::Biological sciences::Biochemistry
在线阅读:	https://hdl.handle.net/10356/152387

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