Investigating novel mechanisms of drug resistance in Plasmodium falciparum

Due to widespread drug resistance undermining antimalarial eradication efforts, there is an urgency to develop new drugs. Drug repurposing was adopted, with drug L selected as a candidate drug. Lack of observable hemozoin, which is a unique resistant phenotype, and discovery of A257T mutation in Pla...

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Bibliographic Details
Main Author: Ng, Shyan Poh Shuang
Other Authors: Peter Preiser
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/153285